Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC). This ...

Image Caption: Dysregulation of lipid metabolism promotes EMT (by Figdraw). Down-regulation of ELOVL2 promotes EMT in breast cancer by up-regulating expression of SREBP1/2. Genes & Diseases ...

The findings suggest that lipid metabolism may play a central role in maintaining a healthy immune system as we age. The researchers analyzed gene and protein expression, along with lipid profiles, in ...

The accumulation of dysfunctional giant mitochondria is a hallmark of aged cardiomyocytes. This study investigated the core mechanism underlying this phenomenon, focusing on the disruption of ...

The Farese & Walther laboratory investigates cellular lipid and energy metabolism, in particular the mechanisms and physiology of neutral lipid synthesis and storage in lipid droplets. More broadly ...

A healthy liver controls lipid metabolism by oxidising fatty acids and secreting bile for fat digestion. In hepatic steatosis, hepatocytes accumulate excess triglycerides, which impede the liver's ...

The role of glioma cellular metabolism in response to oncolytic herpes virus (oHSV) therapy remains to be studied. Here the authors report that oHSV induces metabolic reprogramming in IDH wildtype ...

This book provides a broad introduction to algorithms for decision making under uncertainty. We cover a wide variety of topics related to decision making, introducing the underlying mathematical ...

Secondary metabolism consists of metabolic pathways and products of metabolism that are not absolutely required for the survival of the plant. Secondary metabolism is responsible for many ...

Sugary drinks can also negatively affect your metabolism GETTY Baked goods, cereals, ice cream, chocolate and sweets should all be limited if trying to reduce your consumption of added sugar. Slimmers ...