Liver fibrosis plays a central role in the progression of chronic liver diseases. Despite this, no medications are currently approved specifically for the treatment of Liver fibrosis (1 ...

Fibrosis prediction is an essential part of the assessment and management of patients with chronic liver disease. Blood-based biomarkers offer a number of advantages over the traditional standard ...

Liver fibrosis is a consequence of the sustained inflammatory processes underpinning chronic liver disease. Here authors show that autophagy in CD4 T cells is an important process in preventing ...

Mar. 12, 2025 — Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now ...

Liver fibrosis is a key process in the progression of chronic liver diseases. However, there are currently no drugs specifically designed to treat liver fibrosis. Our Phase 2 trial of hydronidone for ...

1 Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China 2 Department of Gastroenterology, Shanghai Changzheng Hospital, Navy Military Medical ...

While often asymptomatic in its early stages, the condition can lead to severe complications such as liver inflammation, fibrosis, cirrhosis, and even liver cancer if left unchecked. Non-alcoholic ...

Sensitivity is the likelihood of correctly determining the presence of disease in the whole population that has the disease (true positive rate) whereas specificity is the likelihood of correctly ...

If untreated, NAFLD can silently progress to more serious conditions such as non-alcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, and even liver failure. However, the good news ...

However, it can progress over time to more serious liver conditions, including: Steatohepatitis (inflammation of the liver) Fibrosis (scarring of liver tissue) Cirrhosis (advanced scarring and poor ...

With ‘World Liver Day’, having just gone by, this is the right time to talk about the body’s ‘master regulator’, playing key roles in food digestion, body metabolism and detoxification.