In their article published in Nature Methods, the researchers applied PERISCOPE to execute three whole-genome CRISPR screens to create an open-source atlas of cell morphology. The study is the ...

Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy for patients with acute myeloid leukemia (AML ...

Shaanxi Key Laboratory of Macromolecular Science and Technology, Xi’an Key Laboratory of Hybrid Luminescent Materials and Photonic Device, MOE Key Laboratory of Material Physics and Chemistry under ...

When interacting with an APC, T lymphocyte morphology changes drastically: the cell moves on the APC surface, develops invadosome-like structures which push into the cortex of the APC (20–22), spreads ...

In this context, lymphocytes are classified as cells exhibiting amoeboid motility. Indeed, their motility characteristics are comparable to those described in the Dictyostelium discoideum amoeba. The ...