Lymphoid proliferations are traditionally thought to be either benign conditions (reactive hyperplasia and lymphadenitis) or malignant lymphomas. However, not all lymphoid lesions at present can ...

While it is known that chimeric fusion proteins often drive constitutive kinase signaling in leukemic cells, few data exist revealing how these proteins perturb lymphoid development and contribute ...

A recent Nature Immunology study explores the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during viral infection. Study: Temporal Profiling of ...

AtLP are conditions in which it is not possible to differentiate between the benign and the malignant nature of a given lymphoid infiltrate. The descriptive term AtLP may be used as an interim ...

GvL mainly occurs in lymphoid tissues, such as bone marrow and lymph nodes, where the malignant hematological cells reside. GvHD, by contrast, occurs throughout the body after donor T cells become ...

Chemotherapy remains the primary treatment approach for paediatric cancer patients, with nearly 73% of cases undergoing this ...

When someone has cancer or a chronic infection, their body may form tertiary lymphoid structures near or within the cancer. The structures contain immune cells—predominantly B cells—and ...

Anthony Stein, MD, assessed total marrow and lymphoid irradiation with post-transplant cyclophosphamide in patients with ...

Bioheng Therapeutics US LLC ("Bioheng"), a clinical-stage biotech company dedicated to developing innovative universal CAR-T cell therapies, today announced that the U.S. Food and Drug Administration ...