Keywords: adult-onset Still's disease (AOSD), macrophage activation syndrome (MAS), hemophagocytic lymphohistiocytosis (HLH), HScore, MS score, cytomegalovirus (CMV) infection Citation: Long T, Xu J, ...

1 Università degli Studi di Genova and Istituto Giannina Gaslini, Genoa, Italy 2 Istituto Giannina Gaslini, Genoa, Italy ...

While AOSD can often be managed with immunosuppressive therapy, it is sometimes complicated by macrophage activation syndrome (MAS), a severe and potentially life-threatening hyperinflammatory ...

The study’s small size limits interpretation, but it remains the largest real-world data available, experts said.

Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an ...

Hemophagocytic lymphohistiocytosis (HLH) is an inflammatory syndrome characterised by unregulated macrophage and T-lymphocyte activation, resulting in cytokine overproduction and subsequent ...

One of the worst complications of adult-onset Still's disease is macrophage activation syndrome (MAS), which can be fatal. In fact, it was fatal for two patients in the conventional DMARD group.

new data on emapalumab for macrophage activation syndrome, and new drug approvals, Susan Shenoi says. Medscape Medical News, March 20, 2025 Recombinant Zoster Vaccine Effective in Patients With RA ...

PHST001 has shown promising preclinical results, demonstrating macrophage activation, tumor size reduction, and a favorable safety profile. CD24 is a critical mechanism for tumor immune evasion, and ...