A significant aspect of this field is the understanding of memory T cells, particularly tissue-resident memory T cells (TRM cells), which provide localized protection against pathogens and play a ...

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent respiratory diseases.

A groundbreaking study published in Nature reveals how tissue-resident memory CD8 T cells in the small intestine take on ...

Meanwhile, the adaptive system, consisting of T and B cells, responds more slowly, targeting specific antigens and generating long-lived memory cells to enable a quicker, stronger secondary response.

Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of ...

Researchers at the University of Colorado Anschutz Medical Campus have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation—and relocation—as they fight infections in the small intestine.

While naïve T cells lacked the disease-fighting imprinting of memory cells, they became more effective when RUNX2 was added. They also lived longer and the gene protected them against exhaustion ...

Although CAR T-cell treatment can lead to clinical remissions in patients with hematological malignancies, relapse rates ultimately remain high. Previous research has found that T memory stem cell ...