Despite treatment, morbidity and mortality from neonatal sepsis remain high ... An expanded understanding of the complex pathophysiology of sepsis in infants may lead to novel therapeutic ...

The retrospective cohort study analyzed serial blood samples from 252 patients (111 pediatric, 72 maternity, and 69 neonatal cases) with suspected sepsis. Patients were classified by infection ...

The difference in neonatal presentation may be more on a ... Inflammation and coagulation are closely linked in sepsis. Inflammatory mediators generate tissue factor expression and initiate ...