Glioma is a malignant tumor of the central nervous system (CNS). Currently, effective treatment options for gliomas are still lacking. Neutrophils, as an important member of the tumor microenvironment ...

Further bioinformatics analysis revealed that LCN2 involved in functions of neutrophils, including neutrophil degranulation, neutrophil activation involved in immune response, and neutrophil ...

Targeting these blunted responses may offer a new paradigm for treating CAP, but modifying neutrophil behaviour is challenging; reducing their numbers or inhibiting their function is associated with ...

The hub genes are the most interconnected genes in each module, which are therefore potential master regulators. The Pink module was enriched (corrected p<0.05) in Neutrophil Degranulation, an ...

Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma (PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune system. Here, we aimed to ...

List all available databases from Enrichr.

These antibodies bind to specific components of neutrophils and monocytes (myeloperoxidase (MPO) and proteinase 3 (PR3)) and trigger their degranulation which cause the endothelial injury.1 PD-1, ...

Neutrophils undergo a respiratory burst with the production of reactive oxygen species, as well as undergoing degranulation and the release of a range of inflammatory proteins, proteases, and other ...

BACKGROUND Airway inflammation, with recruitment of neutrophils to the airway lumen, results in purulent secretions and a variety of potential adverse consequences for patients with chronic bronchitis ...