Neutrophils play a crucial role in the immune response, acting as the most abundant white blood cells responsible for frontline defense against infections ...

These contrasting effects underscore IL-17’s pivotal but complex influence in disease pathogenesis and bone homeostasis. Myeloperoxidase and NETs generated from IL-17-activated neutrophil ...

However, the molecular mechanisms regulating neutrophil responses and their pathological relevance in post-stroke complications remain unclear. In this study, we investigated the involvement of ...

Targeting these blunted responses may offer a new paradigm for treating CAP, but modifying neutrophil behaviour is challenging; reducing their numbers or inhibiting their function is associated with ...

In the article by Lee et al, “Neutrophil CRACR2A Promotes Neutrophil Recruitment in Sterile Inflammation and Ischemic Stroke,” which published online on November 27, 2024, and published in the March ...

High or low levels of either one can indicate health problems. However, the number of neutrophils to lymphocytes is an essential biomarker. The neutrophil-to-lymphocyte ratio (NLR) reveals the ...

China: A recent study has illuminated the potential of the platelet-to-neutrophil ratio (PNR) as a diagnostic tool in identifying diabetic macular edema (DME), a vision-threatening complication of ...

Intraocular inflammation was evaluated by histopathological scoring. Frequencies of Th1/Th17 cells were measured by flow cytometry. Concentrations of IFN-γ/IL-17A, neutrophil elastase (NE) and ...

Pathway analysis of the lamina propria fraction indicated that both males and females have downregulation of immune-related Th1, Th2, and granzyme A signaling pathways, and upregulation of oxidative ...