Xeroderma pigmentosum (XP) is an autosomal recessive condition resulting from defects in the nucleotide excision repair pathway, causing heightened ultraviolet radiation sensitivity and significantly ...

Ovarian cancer is a relatively manageable malignancy when diagnosed at an early stage, but late-stage detection almost always translates into a poor prognosis. Researchers have been vigorously ...

SCNU Environmental Research Institute, Guangdong Provincial Key Laboratory of Chemical Pollution and Environmental Safety & MOE Key Laboratory of Theoretical Chemistry of Environment, South China ...

Head and neck cancer comprises a group of biologically similar cancers that start in the lip, oral cavity (mouth), nasal cavity (inside the nose), paranasal sinuses, pharynx and larynx. Most head ...

On Wednesday, April 30th, SEED’s pharmacology group will present their work titled, “Targeting Ewing sarcoma with a novel RBM39 degrader: DNA damage repair pathway effects”, related to SEED ...

Presentation Details Title: Anti-cancer effect of Cyclin A/B RxL inhibitors is mediated in part by disruption of the ATR/Chk1 DNA repair pathway Session: Late-Breaking Research: Experimental and ...

On Wednesday, April 30 th, SEED’s pharmacology group will present their work titled, “Targeting Ewing sarcoma with a novel RBM39 degrader: DNA damage repair pathway effects”, related to SEED’s ...

The poster will present new mechanistic insights into the anti-cancer activity of cyclin A/B RxL inhibitors, including their impact on DNA repair pathways and mitotic progression in E2F-high cancers.

Tardigrades are eight-legged, translucent, microscopic animals. They crawl within dirt, moss, and lichen, and also live in the world’s harshest regions such as mountaintops, the deep sea, and the ...