Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

DNA Synthesis Market, valued at a remarkable USD 2.89 billion in 2022, is set to embark on an unprecedented growth trajectory, projecting a robust Compound Annual Growth Rate (CAGR) of more than 19.63 ...

综合研究结论和讨论部分，这项研究首次全面地揭示了 WSSV 感染对虾后，葡萄糖和谷氨酰胺代谢重编程促进核苷酸从头合成的详细机制。不仅明确了谷氨酰胺在支持病毒复制方面的关键作用，还发现 Ras - PI3K - Akt - mTOR 通路并非是调控这一过程的唯一机制。这一成果为深入理解 WSSV 的致病机制提供了全新视角，也为开发针对 WSSV ...

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in ...

Author(s): Timothy Quinn, George F. Wilhere, and Kirk L. Krueger ...

Chemical modification describes the modification, addition or removal, through chemical reaction, of any of a variety of macromolecules, including proteins and nucleic acids. It refers to the use ...

including its newly commissioned automated small molecule synthesis platform." The size of the deal means that, if it is consummated, it will top prior M&A deals involving AI in drug discovery ...

Hepatitis B affects almost 300 million people worldwide, according to GSK, and while nucleoside/nucleotide analogue (NA) drugs to treat it are available – such as Gilead’s polymerase inhibitor ...