Fully grown oocytes within the ovary are already much larger than sperm, and the future egg retains most of this volume as it passes through meiosis. As a consequence, only one functional oocyte ...

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China ...

In their manuscript entitled "BEND2 is a crucial player in oogenesis and reproductive aging", the authors present their findings that full-length BEND2 is important for repair of meiotic double strand ...

The molecular functions predominantly associated with these genes included protein and DNA binding. These SRGs also featured in pathways relevant to cell cycle regulation, response to Human T-cell ...

During early meiosis, recombination initiates with SPO11-mediated DSB formation ... for 2 h at room temperature in a closed humid chamber. Oocyte nuclei spreading was prepared from fresh fetal and ...

他们发现，在与跗骨长度相关的进化速率变化中，一些基因功能项表现出显著的富集，如卵母细胞减数分裂（oocyte meiosis）和心肌细胞中的肾上腺素信号传导（adrenergic signalling in cardiomyocytes）。这些基因功能项的富集可能与鸟类在K–Pg过渡之后的快速生态分化 ...

Expert Rev of Obstet Gynecol. 2008;3(4):555-563. The complex process of follicular and oocyte maturation can be affected by a number of tobacco constituents. Cadmium, polycyclic aromatic ...

Objectives: Lung cancer is one of the most common cancers worldwide and it is the leading cause of cancer-related mortality. Despite the treatment of patients with non-small cell lung carcinoma (NSCLC ...

Until now, it has been unclear why this happens. A research team led by Max Planck director Melina Schuh, head of the ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...