Furthermore, clinical translation of existing models faces significant challenges as the models fail to simulate the dynamic processes such as the imbalance between osteolysis and osteogenesis, tumor ...

"This patient was suffering from femoroacetabular impingement (FAI), a condition where abnormal contact between the bones — the femur and acetabulum — causes pain and can damage the joint ...

After years of vigorous testing, including genetic testing and three MRIs, and being misdiagnosed with Kohler’s disease, Adelaide was diagnosed with multicentric carpotarsel osteolysis ...

X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7 ...

TNFRSF11A encodes the receptor activator of NFκB (RANK), which is critical for normal osteoclast formation; genetic variants in this gene result in familial expansile osteolysis, a Paget-disease ...

Objective To evaluate the clinical efficacy and effectiveness of using 3D printing to develop medical devices across all medical fields. Design Systematic review compliant with Preferred Reporting ...

For more serious separations, surgery is needed followed by rehabilitation and muscle strengthening. Distal clavicle osteolysis is an overuse injury caused by weightlifting or other repetitive ...

A recent study has identified a promising new approach to treating osteonecrosis of the femoral head (ONFH), a painful bone disease that leads to joint collapse. Researchers found that exosomes ...

The first 3 components are known as the Primary Changes. These are assessments of the conformation of the hip joint. The poorer the fit of the femoral head (“ball”) to the acetabulum (“socket”) the ...

为解决全髋关节置换术（THA）后因磨损诱导的骨溶解导致翻修手术负担重的问题，研究人员开展了地诺单抗（Denosumab）治疗假体周围骨溶解的随机、双盲、安慰剂对照试验。结果显示试验可行但入组慢，虽未达主要结局，但为后续研究奠定基础。 在骨科领域，全 ...