综合研究结果和讨论部分，该研究首次揭示了 SYT1 在心脏肥大中的重要保护作用。SYT1 缺乏会通过激活 p38 MAPK 通路，加重压力过载诱导的心脏肥大、纤维化、功能障碍以及心肌细胞凋亡。这一发现为深入理解心脏肥大的发病机制提供了新的视角，也为开发治疗心脏肥大的新策略提供了极具潜力的靶点，有望在未来为心血管疾病的治疗带来新的突破，具有重要的理论和临床意义。

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

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研究人员开展了 OsBSKs（BRASSINOSTEROID - SIGNALING KINASES）和 OsMAPKs（MITOGEN ACTIVATED PROTEIN KINASE ... 此外，OsBSK 3 和 OsBSK 2 均与 OsMKKK10 相互作用，在植物细胞中间接激活 OsMAPK6。值得注意的是，MAPK 级联成分的突变，如 smg2 - 1（osmkkk10 ...

NRF2 siRNA attenuated TMPZ’s anti-inflammatory and pyroptosis-inhibitory effects, confirming the involvement of the NRF2 pathway. Conclusion: TMPZ mitigates AP-induced inflammation and injury by ...

脂多糖（Lipopolysaccharides, LPS）（M9524）是革兰氏阴性细菌细胞壁的主要成分，它在免疫学、微生物学和炎症研究领域有着重要的应用。AbMole提供高品质抑制剂、细胞因子、人源单抗、靶点蛋白、天然产物、荧光染料、多肽、化合物库 ...

Glycolytic capacity efforts are short, high-intensity efforts lasting 1–3 minutes where glycolysis is the primary energy ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Hair follicles continuously cycle through anagen (growth), ...