Department of Nutriology, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China Hubei Key Laboratory of Lipid Chemistry and Nutrition, Oil Crops Research ...

综合研究结果和讨论部分，该研究首次揭示了 SYT1 在心脏肥大中的重要保护作用。SYT1 缺乏会通过激活 p38 MAPK 通路，加重压力过载诱导的心脏肥大、纤维化、功能障碍以及心肌细胞凋亡。这一发现为深入理解心脏肥大的发病机制提供了新的视角，也为开发治疗心脏肥大的新策略提供了极具潜力的靶点，有望在未来为心血管疾病的治疗带来新的突破，具有重要的理论和临床意义。

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

Search for other works by this author on: ...

It plays a vital role in activating or inhibiting pathways such as MAPK and PI3K/Akt, modulating apoptosis-related proteins like ... Similarly, in IRI, apoptosis Signal-regulating Kinase 1(ASK1) is ...

HPK1 mediates neutrophil responses and NET aggregation through NF-κB/STAT3/p38-MAPK signaling pathways and GSDMD cleavage. HPK1 promotes post-stroke neutrophil mobilization during acute phase by ...

Acacetin not only alleviates vascular inflammation by regulating the p38 MAPK and NF-κB pathways, but also restores mitochondrial function and reduces endothelial cell apoptosis through activating the ...

研究人员开展了 OsBSKs（BRASSINOSTEROID - SIGNALING KINASES）和 OsMAPKs（MITOGEN ACTIVATED PROTEIN KINASE ... 此外，OsBSK 3 和 OsBSK 2 均与 OsMKKK10 相互作用，在植物细胞中间接激活 OsMAPK6。值得注意的是，MAPK 级联成分的突变，如 smg2 - 1（osmkkk10 ...