Furthermore, the phosphorylation levels of p38 and JNK in the MAPK pathway were significantly reduced, suggesting a key mechanism for its therapeutic effects. Discussion: These findings provide strong ...

We thank Professor John L. Rubenstein for his comments, suggestions, and edits. We are grateful to Professor Hua Han for sharing the Rbpj floxed mice, and Professor Jean M. Hebert for sharing ...

Billionaire Elon Musk's Electric Vehicle (EV) giant Tesla Inc. is hiring in India; a sure sign that it plans to enter the market, according to a Bloomberg report. Prime Minister Narendra Modi and ...

Here we report an activity-dependent stabilization of the MAP kinase (MAPK) pathway, prominent in hippocampal ... stimulus-specific responses of MAPK signaling in activity-dependent neuronal ...

That change was linked to a rise in a modified form of cholesterol known as oxysterol. Lowering oxysterol, in both animal models and human stem cells, freed the trapped ABCA1 and restored the pathway ...

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Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention, National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary, IRDR International Center of ...

When mice are full and eat sugar, these nerve cells not only release signaling molecules that stimulate ... sugar even beyond fullness. This opioid pathway in the brain was specifically activated ...

Pathway Sports and Entertainment, a new company “focused on monetizing athlete NIL rights,” is launching into the space by “providing players with four-figure guarantees as part of video game NIL ...

impact of MAPK pathway pathogenic variants” 的论文。这篇论文在罕见病治疗研究领域意义重大，它深入探究了 MEK 抑制剂在 Erdheim-Chester 病（ECD）治疗中的疗效与 MAPK 通路致病突变之间的关联，为 ECD 的精准治疗提供了关键依据，有助于指导临床医生更合理地选择治疗方案 ...

If a vogue for virtue signaling defined the 2010s and early 2020s, peaking in 2020 during the feverish summer of protest and pandemic—a period in which pronouns in bio, land acknowledgments ...