资讯

T cells are a type of white blood cell that is central to your immune defense. Four types that serve different functions include: CD4 and CD8 are two different types of glycoprotein found on the ...
CD4⁺和 CD8⁺调节性 T 细胞(Treg)在免疫调节中发挥关键作用,但二者存在诸多差异。 CD4⁺ Treg 表达转录因子 FOXP3,维持其抑制功能;CD8⁺ Treg 在人类中表达杀伤细胞免疫球蛋白样受体(KIRs),部分还表达颗粒酶 B(GZMB) ,在免疫调控中起重要作用。在人 ...
在免疫系统中,CD4⁺和CD8⁺调节性T细胞(Treg)扮演着至关重要的角色,二者在功能上却存在显著差异。首先,从细胞表型来看,这两个细胞群体的标志物不同。CD4⁺Treg通过表达转录因子FOXP3来维持其抑制性功能,而CD8⁺Treg则在人类中表达杀伤细胞免疫球蛋白样 ...
研究样本来自健康供体的外周血单个核细胞(PBMC)。 研究结论表明,MTBVAC 在与 PBMC 相互作用的第一周就能激发有效的早期免疫反应,激活包括 CD4 和 γδ T 细胞在内的效应淋巴细胞群体,这些细胞的表型与能够控制分枝杆菌感染的个体中观察到的一致,同时还 ...
unless stated otherwise): PB-labelled anti-CD4; PE/Cy7-labeled anti-CD8 (HIT8a; BD); APC-H7-labeled anti-CD25 (M-A251; BD); Qdot-605-labeled anti-CD3 (SK7; Invitrogen); and Live/Dead™ Fixable Aqua ...
We apply ELSA to the PBMC data set, which has several different cell types including B cells, CD4 and CD8 T-cells, dendritic cells, Natural Killer cells, and myeloid cell types. We find that ...
5 Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore 6 Department of Diagnostic Radiology, Singapore General Hospital, Singapore 7 Department of Nuclear ...
This vignette demonstrates how to map scRNA-seq and scATAC-seq data to Azimuth reference datasets directly in R, without the need to upload data into the web application.
They analyzed 82 formalin-fixed, paraffin-embedded bladder CIS samples from BCG-treated patients. Responders and non-responders were classified based on relapse. Tissue sections were immunostained for ...
研究结果表明,低剂量 IL-2 在糖尿病和 OIR 小鼠模型中展现出了积极的治疗效果。 在 Tregs 和 CD8 + T 细胞方面,低剂量 IL-2 显著增加了血液和脾脏中 CD4 + CD25 + Foxp3 + Tregs 的数量,增强了 Tregs 的功能,提高了细胞毒性 T 淋巴细胞相关蛋白 4(CTLA4)、程序性细胞死亡 ...