Conversely, a limitation of the MTA-seq method is that the DNA sequence around the target SNPs must be known in order to design primers. Comparison of MTA-Seq With Other Non-commercial SNP-Genotyping ...

A method for genetically barcoding Drosophila is developed and used to tag defined cell populations in vivo for single-cell transcriptomics experiments and to enable multiplexed behavioral analysis.

The platform enables direct, unbiased genome-wide identification and quantification of the exact position of double strand DNA breaks in edited cells.

Their clinical testing is often multitiered; diagnostic testing begins with methylation-specific multiplex ligation-dependent probe amplification or methylation-sensitive PCR and then proceeds to ...

Purpose: To seek novel diagnostic approaches, we improved the workflow of cell-free DNA (cfDNA) sequencing and evaluated its feasibility in vitreoretinal lymphoma (VRL) specimens; the profile of ...

The innovation, he says, could transform the way scientists measure and address genomic breaks in gene-editing systems.

Cell line development plays a pivotal role in the manufacturing of therapeutic proteins, vaccines and other biologics.

Like a language, they encode information. But humans can’t easily read or interpret these instructions for life. We cannot, at a glance, tell the difference between a DNA sequence that functions in an ...

or chromatin immunoprecipitation (ChIP), followed by region-specific quantitative PCR (qPCR) or by genome-scale microarray or DNA sequencing. These can be carried out by incorporating DNA ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

Learning about your genetics and ancestry is easier than ever. All you need to do is choose from the many DNA ancestry tests available online, receive your kit and send back the required DNA samples.

SOLiD: Sequencing by Oligonucleotide Ligation and Detection.