The introduction of inhibitors of the cyclic GMP phosphodiesterase (PDE) 5 into clinical urology is mainly the result of the characterization of the physiology of nonvascular and vascular penile ...

Phosphodiesterase 5 (PDE5) is a cGMP-specific hydrolytic enzyme highly expressed in pulmonary vascular smooth muscle cells. Novel PDE5 inhibitor for pulmonary arterial hypertension identified | ...

Learn how common medications like nitroglycerin, antidepressants, and hormone therapies can trigger migraine attacks.

New York Post may be compensated and/or receive an affiliate commission if you click or buy through our links. Featured pricing is subject to change. Let’s cut to the chase: erectile dysfunction ...

The serendipitous discovery that inhibiting type 5 phosphodiesterase (PDE5) using sildenafil, a potent PDE5 inhibitor (PDE5i) initially developed for cardioprotection, introduced the possibility of ...

endothelin receptor antagonists and phosphodiesterase type 5 (PDE5) inhibitors. With the approval of the soluble guanylate cyclase stimulator riociguat, an additional drug class has become available ...

From your mental state to your eating habits, a range of factors can and will influence the effectiveness of Viagra and other phosphodiesterase type 5 inhibitors like Cialis and Stendra.

Biodiversity-derived molecules, namely those extracted from medicinal plants, are promising sources of toxin inhibitors that can minimize the deleterious consequences of SBEs. In this review, we ...