MiR-34a has been shown to regulate cellular apoptosis, autophagy, inflammation, senescence and remodeling in various cardiac and vascular tissues and cells through Smad4/TGF-β1, FOXO3/PUMA, ...

Apoptosis occurs in a wide range of human diseases. In animal models of virus-induced disease, apoptosis correlates with viral titre and can be found in areas targeted by viral infection, which ...

Apoptosis and autophagy constitute the two self-destructive processes by which supernumerary, damaged or aged cells and organelles are eliminated. Beyond this homeostatic function, autophagy is ...

FIGURE 2. Rho GTPase signaling pathways regulating neuronal survival. Rho activates a downstream ROCK/PTEN pathway that indirectly inactivates the pro-survival protein Akt to suppress neuronal ...

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