X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7 ...

Linkage analysis was originally used to identify familial Paget disease genes. One study indicated that about 29% of families with a history of Paget disease have a mutation in the sequestosome 1 ...

Juvenile Paget disease (JPD) is a very rare disease, mainly caused by biallelic inactivating mutations in the TNFRSF11B gene that encodes osteoprotegerin. Owing to its rarity, the treatment of JPD is ...

Considering taking supplements to treat paget disease? Below is a list of common natural remedies used to treat or reduce the symptoms of paget disease. Follow the links to read common uses ...

New Key Genes in Parkinson's Disease Identified Using CRISPR Technology Apr. 11, 2025 — A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic ...

New Study Links Lower Proportions of Certain Sleep Stages to Brain Changes Associated With Alzheimer's Disease Mar. 31, 2025 — New research reveals that lower proportions of specific sleep ...

Paget Brewster's Criminal Minds arrival boiled down to one original cast member's exit, which had to do with the latter's detest for LA.

Paget Brewster’s journey to becoming Emily Prentiss on Criminal Minds was a deliberate move toward stability. After years of bouncing between roles and living out of suitcases, Brewster reportedly ...