X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7 ...

Linkage analysis was originally used to identify familial Paget disease genes. One study indicated that about 29% of families with a history of Paget disease have a mutation in the sequestosome 1 ...

Juvenile Paget disease (JPD) is a very rare disease, mainly caused by biallelic inactivating mutations in the TNFRSF11B gene that encodes osteoprotegerin. Owing to its rarity, the treatment of JPD is ...

Considering taking supplements to treat paget disease? Below is a list of common natural remedies used to treat or reduce the symptoms of paget disease. Follow the links to read common uses ...

Two people in Oregon have died from a rare, progressive brain disorder similar to "mad cow disease" that leads to dementia and is %100 fatal. The Hood River County Health Department confirmed the ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease ...

New Study Links Lower Proportions of Certain Sleep Stages to Brain Changes Associated With Alzheimer's Disease Mar. 31, 2025 — New research reveals that lower proportions of specific sleep ...

Following the success of recent clinical trials, several major infectious disease agencies updated treatment guidance for drug-susceptible and drug-resistant tuberculosis for adolescents and adults.