In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis—a primary driver of cardiovascular death worldwide—in large mammals, a study suggests.

There are many health problems relating to the heart and among them, a serious one is Atherosclerosis – a silent killer. There is an urgent need to understand this condition to enable us to take ...

Join Drs Maureen McMahon and Michael Garshick as they discuss cardiovascular disease in patients with systemic lupus erythematosus, focusing on hidden risk and challenging clinical scenarios.

"The emergence of DT-109 as a dual-action drug capable of treating both MASH and the vascular complications associated with atherosclerosis marks a significant advancement in the treatment ...

Given the contribution of EC-derived EVs to atherosclerosis, this model represents the first in vivo murine approach to tracking intercellular EC-EV communication within the plaque. It provides an ...

A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis — a primary driver of cardiovascular death worldwide — in large mammals, a study suggests.

Caris A. Wadding-Lee https://orcid.org/0000-0002-8194-8543 Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati ...

You will be redirected to our submission process. Given the success of Volume I of this Research Topic, and how rapid the subject area is evolving, we are pleased to announce the launch of ...

Inflammation is a biological response to harmful stimuli, such as pathogens, damaged cells or irradiation. It is a protective attempt by the organism to remove injurious stimuli and to initiate ...

The company’s Repatha (evolocumab) was added to optimised statin therapy in a phase 3 trial, and resulted in statistically significant regression of atherosclerosis in patients with coronary ...