A picture of a biological membrane that includes ... membrane lipids is involved in the sorting process—namely, that lipid domains in the plane of the membrane termed 'rafts' have high affinity ...

what really prevents us from constructing a precise picture of signaling networks in general and of lipid signaling in particular is the lack of information on molecule numbers and location.

Cancer cells are altering how this lipid is metabolized, which in turn distorts the 'eat me' signals that malignant cells usually produce. This paints a very different picture of the role lipids ...