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《Nature Genetics》PROX1积极抑制细胞命运可塑性,保护肝细胞身份 ...
本研究确定了在成熟细胞类型中抑制交替谱系的候选保护性抑制转录因子,并提供了Prox1在重编程、再生和癌症过程中在肝细胞中发挥这种功能的功能证据。 德国癌症研究中心(German Cancer Research Center,DKFZ)和 DKFZ-ZMBH 联盟的研究人员在《Nature Genetics》期刊上 ...
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