Seropositive rheumatoid arthritis may be protective against the development of PAH, based on results of Mendelian randomization analyses.

Pulmonary arterial hypertension is a disease of the pulmonary vasculature, resulting in elevated pressure in the pulmonary arteries and disrupting the physiological coordination between the right ...

How best to manage symptomatic patients with chronic thromboembolic pulmonary disease (CTEPD) in the absence of pulmonary hypertension is not resolved. Right ventricular–pulmonary artery coupling ...

ET indicates endothelin; ETA, endothelin type A; IP, prostaglandin I2; NO, nitric oxide; PAH, pulmonary arterial hypertension; PDE-5, phosphodiesterase type 5; and sGC, soluble guanylate cyclase.

Inhibiting GLS1 reduced high blood pressure in the right side of the heart of PAH rats and improved various measures of heart ...

F-FAPI PET -- can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker for disease progression. This approach ...

Pulmonary arterial hypertension (PAH) is commonly associated with congenital heart disease (CHD) and relates to type of the underlying cardiac defects and repair history. Large systemic to pulmonary ...

4 University of Giessen and Marburg Lung Center (UGMLC), member of the German Center of Lung Research (DZL), Giessen, Germany Until recently, three classes of medical therapy were available for the ...

Department of Therapeutic Strategy for Heart Failure, Tokyo, Japan 3 Graduate School of Medicine, The University of Tokyo, Department of Allergy and Rheumatology, Tokyo, Japan Background: Connective ...

Pulmonary hypertension is characterized by pulmonary arterial remodeling that results in increased pulmonary vascular resistance, right ventricular failure, and premature death. It is a threat to ...