In animal models, inhibition of neutrophil chemokines or disruption of these chemokine gradients in the lung attenuates ALI. Molecules associated with enhanced wound closure, such as epithelial ...

Individuals with asthma and chronic obstructive pulmonary disease (COPD) were more vulnerable than healthy controls to ...

Firstly, we found that ATG suppressed PQ-induced pulmonary fibrosis by blocking the epithelial-mesenchymal transition (EMT). ATG reduced the expressions of Vimentin and α-SMA (lung fibrosis markers) ...

A better understanding of inflammation and lung immunity over the past two decades has led to new, innovative treatments for ...

A discovery offers new hope in the battle against pulmonary fibrosis, a debilitating lung condition that progressively makes it harder for patients to breathe. Scientists have pinpointed proteins in ...

umcg.nl Background WNT signalling is activated during lung tissue damage and inflammation. We investigated whether lung epithelial expression of WNT ligands, receptors (frizzled; FZD) or target genes ...

A discovery at Duke-NUS Medical School offers new hope in the battle against pulmonary fibrosis, a debilitating lung ...

Airway Reopening,Surface Tension,Pulmonary Epithelial Cells,Shear Stress,Air-liquid Interface,Boundary Element Method,Cells In Region,Channel Walls,Computational Investigation,Dynamic Surface ...

As such, it matches the huge surface areas of the alveolar epithelium to the pulmonary blood capillaries. The lung’s constant exposure to the exterior necessitates a competent immune system, as ...

Background Cigarette smoking contributes to lung remodelling in chronic obstructive pulmonary disease (COPD). As part of remodelling, peribronchiolar fibrosis is observed in the small airways of ...