Background: The use of appetite suppressants in Europe has been associated with the development of primary pulmonary hypertension (PPH). Recently, fenfluramine appetite suppressants became widely ...

TX45 improved both left ventricular function and pulmonary hemodynamics in patients with Group 2 Pulmonary Hypertension in Heart Failure with ...

Objective Systemic sclerosis-associated pulmonary arterial hypertension differs from idiopathic pulmonary arterial hypertension ... This study also underlines a prominent role of PDGF in the ...

Pulmonary arterial hypertension (PAH) is characterized by significant morbidity and mortality ... All these new findings and updated reviews collectively contribute to advancing our understanding of ...

Pulmonary Arterial Hypertension Overview When measured ... on the basis of shared pathophysiology, clinical presentation, and available treatments. The epidemiology section provides insights ...

and pulmonary hypertension may be particularly relevant to the pathophysiology heart failure in patients with preserved ejection fraction, there is compelling rationale for extending the ...

This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading ... Researchers Identify Over 2,000 Genetic Signals Linked to Blood ...

This Research Topic aims to deepen the understanding of the role of oxidative and nitrosative stress in the pathophysiology of cardiovascular diseases and pulmonary hypertension. It seeks to explore ...

4 University of Giessen and Marburg Lung Center (UGMLC), member of the German Center of Lung Research (DZL), Giessen, Germany Until recently, three classes of medical therapy were available for the ...

ET indicates endothelin; ETA, endothelin type A; IP, prostaglandin I2; NO, nitric oxide; PAH, pulmonary arterial hypertension; PDE-5, phosphodiesterase type 5; and sGC, soluble guanylate cyclase.