Etiology: The cause of granuloma annulare is unknown. Granuloma annulare can occur at any age, but is seen predominantly in children and young adults. It occurs more frequently in females than males.

A granuloma is a cluster of cells and other tissues that clump together in response to inflammation. They could develop beneath the skin or deep inside the body, such as in the lungs and intestines.

Background: Punctal/intracanalicular plugs on the market nowadays are all designed before clinical use in treating dry eye disease (DED). To provide an individualized lacrimal drainage system ...

This review explores host targets and molecular pathways in the inflammatory granuloma host immune response that may be beneficial as target candidates for HDTs against TB. Mycobacterium tuberculosis ...