The activation of pyroptosis has been shown to have implications ... This highlights the interplay between microbial virulence factors and host immune responses, emphasizing the importance of ...

Methods: Pearson’s correlation coefficient was used to identify pyroptosis- and immune-related differentially expressed lncRNAs (DE-pyrolncRNAs and DE-ImmlncRNAs, respectively). The Cancer Genome ...

Pyroptosis and ferroptosis, as two typical forms of immunogenic cell death, have been shown to activate or modulate the immune system. In previous studies, immunotherapy mediated by pyroptosis and ...

It facilitates the clearance of damaged hepatocytes, preventing secondary injury, and triggers immune responses to eliminate pathogens and damaged cells. Conversely, excessive pyroptosis intensifies ...

In this study, Zaho and colleagues investigate inflammasome activation by E. tarda infections. They show that E. tarda induces the activation of the NLRC4 inflammasome as well as the non-canonical ...

Immune cell death is the process by which an ... programmes or external factors including apoptosis, necrosis, pyroptosis and necroptosis. The Nr4a family of nuclear receptors has been implicated ...

Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong ...

Jan. 28, 2025 — Study reveals how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of both food allergies and intestinal ...

Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...