UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

A study reveals DNA and RNA epigenetics work together as a complementary system for precise gene regulation, crucial for cell ...

Many people follow the golden rules of avoiding direct sunlight between the hours of noon and 3 p.m., staying in […] ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA.

1958年，弗朗西斯・克里克提出了中心法则，提出遗传信息从 DNA 转录为 RNA，再经翻译指导蛋白质合成，随后蛋白质参与生命活动这一流程，看似一气呵成，实则存在问题。 若仔细观察，便会发觉此流程不够简洁，RNA 的存在略显累赘。毕竟，越简单的系统往往越高效、越易实现，繁琐的系统则耗能多且不易形成。 从结构看，RNA 与 DNA ...

By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating ...

Postdoctoral scholar Daniela Soto has earned a prestigious fellowship from HHMI with eight years of funding to study the ...

The quantification of the SARS-CoV-2 genomic RNA was done using RT-ddPCR methods, and the level of LoD indicated that this sequencing method can be used for any RT-qPCR positive clinical sample. The ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a ...

2013). Figure 5. Circularization of the PV genome and initiation of negative-strand RNA synthesis. PV polypeptide and cellular factor poly(C)-binding protein (PCBP) bind to the 5′ UTR cloverleaf, and ...