With increasing interest in developing antifibrotic therapies, there is a need for cell lines that preserve the in vivo phenotype of human HSCs to elucidate pathways of human hepatic fibrosis. We ...

The mechanism by which patients with portal hypertension ... the gradient of the hydrostatic pressure of the free or wedged hepatic vein in hepatic cirrhosis. [22] Various studies have shown ...

Patients with a creatinine clearance of < 30 mL/min and patients with hepatic impairment should avoid duloxetine. Duloxetine should not be recommended as first-line therapy for SUI or DPNP.

The mechanism of enzyme catalysis is similar in principle to other types of chemical catalysis, for instance by involving a combination of several different types of catalysis. Determining enzyme ...