研究人员为探究 SHANK3 在母性行为中的作用，对 Shank3 突变犬研究，发现催产素可改善其母性行为缺陷，为 ASD 治疗提供新思路。 探索自闭症母性行为缺陷的奥秘：Shank3 突变犬与催产素的奇妙关联 在神秘的神经发育领域，自闭症谱系障碍（Autism Spectrum Disorder ...

This manuscript investigates a Shank3-overexpressing mouse model of mania. Authors report disruptions in adult neurogenesis—an increased number of quiescent neural stem cells and excessive ...

由银河脑科学技术有限公司首席科学家刘河生发明的静息态功能磁共振技术，成功绘制出世界上首个全脑功能网络，基于此研发的个体脑功能剖分技术，被《柳叶刀》评价为“神经影像学的转折点”。如今，科技成果成功实现转化，在抑郁症、孤独症、帕金森综合征、失语症、运动障 ...

由银河脑科学技术有限公司首席科学家刘河生发明的静息态功能磁共振技术，成功绘制出世界上首个全脑功能网络，基于此研发的个体脑功能剖分技术，被《柳叶刀》评价为“神经影像学的转折点”。如今，科技成果成功实现转化，在抑郁症、孤独症、帕金森综合征、失语症、运动障碍、睡眠障碍等多种脑疾病的临床试验中均取得了突破性疗效。

Autism spectrum disorders are a group of neurodevelopmental disorders that are characterized by impaired social interaction and communication skills, and are often accompanied by other behavioural ...

通过敲除或敲降与自闭症相关的基因，如TBR1、SHANK3和SYNGAP1，来模拟ASD的神经发育和行为特征。 药理学模型： 使用药物如丙戊酸（valproicacid）处理斑马鱼，模拟环境因素对ASD的影响。 行为学模型： 利用斑马鱼的社交行为、学习能力和运动能力等行为学特点 ...

Synapses play a pivotal role in forming neural circuits, with critical implications for brain functions such as learning, memory, and emotions. Several advances in synaptic research have demonstrated ...

The cerebellum has been repeatedly implicated in gene expression, rodent model and post-mortem studies of autism spectrum disorder (ASD). How cellular and molecular anomalies of the cerebellum relate ...

The purchase and consumption of alcohol and substances often increases during the holiday season, and while some may drink to celebrate, others may drink to suppress their feelings.

Abdominal aortic aneurysm (AAA) is a severe aortic disease for which no pharmacological interventions have yet been developed. This investigation focused on identifying protein‐based therapeutic ...