Quantitative qPCR and immunostaining analyses revealed that BMP4 facilitated MPC differentiation into smooth muscle cells ... progenitor cells (MPCs) could be efficiently harvested was unknown. We ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

A recent study investigates the role of the deubiquitinase OTUB1 in vascular smooth muscle cells (VSMCs) within the context of atherosclerosis, a disease characterized by lipid accumulation and ...

The ECM (extracellular matrix) provides the microenvironmental niche sensed by resident vascular smooth muscle cells (VSMCs ... In all comparisons, there was also upregulation of EV markers, including ...

using single cell RNA sequencing and Time of Flight Mass Cytometry (14, 15) supports the need to study interactions of defined subsets of immune cells with endothelial and vascular smooth muscle cells ...

Correspondence to Dr Zhiqi Zhang, Department of Joint Surgery, Sun Yat-sen University First Affiliated Hospital, Guangzhou 510080, China; zhzhiqi{at}mail.sysu.edu.cn; Dr Weiming Liao; ...

However, what types of heterogenous cancer cells in primary tumour and how they metastasise to the target organs remain largely undiscovered. Design We performed single-cell RNA sequencing and spatial ...

"What we discovered is a specific transporter, a protein on the membrane of airway smooth muscle cells, allows cAMP to leak into the blood," said Reynold Panettieri, one of the study's senior ...

When stimulated by the autonomic nervous system to contract from the release of hormones or other chemical signals, smooth muscle cells shorten via the movement of actin and myosin myofilaments. The ...

However, there is strong agreement that α-SMA is not an exclusive marker for activated PSC. It is also expressed by myofibroblasts, smooth muscle cells and pericytes in blood vessels as well as ...