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Background Lymphangioleiomyomatosis (LAM) is a rare multisystem disease almost exclusively affecting women which causes loss of lung function, lymphatic abnormalities and angiomyolipomas. LAM occurs ...

(1) SY1 aggregation enhances (in terms of number of aggregates) when Sphingolipid biosynthesis is blocked. (2) In a normal cell (where sphingolipid biosynthesis is not hampered), the aggregate of SY1 ...

Here, using a yeast imaging-based screen, we identified 84 potential synphilin-1 (SY1) IB regulators and isolated the conserved sphingolipid metabolic components in the most enriched groups.

Significant diversity in lipid structure exists, with between 1000 and 2000 different lipid species thought ... As major components of lipid rafts, sphingolipid concentration at the plasma membrane is ...

Lisa Schiff became the country’s leading art consultant, and drew her clients close. Then she stole millions from them. Now facing up to 20 years in prison, is she ready to repent? By Sarah ...

Numerous enzymes regulate sphingolipid synthesis and catabolism. Sphingosine kinases (SPHK) catalyze the phosphorylation of sphingosine to form S1P, changing sphingosine’s charge and considerably ...

Can include rhythm, melody, harmony, dynamics, texture, timbre and structure. of the music such as their melody close melodyDifferent pitched notes played one after another making a tune., ...

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The New Jersey Devils have made a flurry of move with the hockey world’s attention turning back toward NHL rosters. The New Jersey Devils have announced that they’ve called up goaltender Tyler ...

February 17, 2025 • The upcoming Augmented Intelligence sale represents the first time a major auction house is focusing entirely on works created using machine learning. Artists have mixed ...

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