By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent continuous stimulation of postsynaptic neurons. There are two types of removal: Re-uptake – the ...

AMPARs can enter or leave the synapse through exocytosis and endocytosis ... AMPARs are probably inserted at sites distant from the synaptic cleft, from which they diffuse laterally within the ...

Serafini and colleagues provide evidence that neuroligin acts as a trans-neuronal signal to induce presynaptic differentiation at neuron–neuron connections in vitro. To form a synaptic ...