Treatment with TNF inhibitors yielded no differences in outcomes vs. other antirheumatic therapies among U.S. veterans with ...

15 Amsterdam Rheumatology and Immunology Centre, Reade, Amsterdam, The Netherlands Objectives We sought to investigate whether genetic effects on response to TNF inhibitors (TNFi) in rheumatoid ...

It was the first partially selective TACE inhibitor to reach phase II clinical trials for the treatment of RA and was tested in the preclinical setting for inflammatory bowel disease. BMS has ...

We believe in the association of multiple factors, which could be caused by the basal disease itself, associated immunosuppressant agents and the use of TNF inhibitors. The pathogenesis of these ...

Our finding that TNF induces sustained chromatin activation in regulatory elements of the genes that escape repression in RA FLS suggests that altering or targeting chromatin states in FLS (eg, with ...

Using glucocorticoids, rituzimab, or certain immunosuppressants to treat connective tissue diseases is associated with ...

The advent of anti-TNF agents as the first approved targeted therapy in the treatment of inflammatory ... and final approval of the version to be submitted. RA, MN, and BS are supported by the CRC-TRR ...

Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions ...

Rheumatoid arthritis (RA) is an inflammatory, autoimmune condition that affects not only joints but also organs, including eyes. While it can have painful and debilitating effects if left untreated, ...