Models were fitted to population data using NMQUAL (https://metruminstitute.org/index.html-validated installation of the NONMEM, version V, level 1.1; GloboMax ...

The parameter and OBJs values for the base 1-, 2-, and 3-compartment models are summarized in Table 1. As found in the separate modeling of the intravenous and nasal data, the 2-compartment model ...

Voriconazole pharmacokinetics was best described by one-compartment PK model with first-order absorption, parameterized by clearance of 4.56 L/h (36.9% CV), volume of distribution of 60.7 L, ...

A one-compartment model adequately described ... this is the first study that investigated the pharmacokinetic features and optimized dosage of polymyxin B in renal transplant patients. AUC 0–24h of ...

Mydriatic microdrops are noninferior to standard drops of a diluted mydriatic mixture when used in infants being screened for ROP.

Elon Musk-led xAI finally unveiled its powerful Grok 3 AI model. The company also announced Grok 3 Reasoning models. Grok 3 outperforms GPT-4o, Claude 3.5 Sonnet, and Gemini 2.0 Pro on AIME 2024, GPQA ...

xAI on Monday unveiled its updated Grok 3 artificial intelligence model, as the Elon Musk-led startup pushes to keep pace with the advanced reasoning and search capabilities in competitors’ models.

The long-awaited Grok-3 has been spotted in the wild. Although this model is not yet available to the public, we managed to access it on the stand-alone Grok platform. We were also able to compare the ...

Daniel Robinson is a writer based in Greenville, N.C. with expertise in auto insurance, loans, warranty options and more. Away from the keyboard, Daniel spends time with his wife and son, plays ...