In frame translation initiation sites within coding sequences drive the expression of N-terminally truncated proteoforms.

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

TC occurs mainly at the translation initiation stage. The initiation factor eIF5B tightly regulates global translation initiation and facilitates the expression of a subset of proteins involved in ...

Alterations in the expression and activity of specific translation factors, and the uncoupling of translational regulation from inhibition by tumour cell stresses, such as hypoxia and nutrient ...

That said, I’m a translation tech skeptic and intended to find all the cracks where this tech could fail. The glasses were adept at translating a basic conversation about K-pop bands.

Meghan I. Podolsky, from the Boston University School of Public Health, and colleagues explored factors associated with semaglutide initiation among commercially insured individuals with obesity ...

21 in JAMA Network Open. Meghan I. Podolsky, from the Boston University School of Public Health, and colleagues explored factors associated with semaglutide initiation among commercially insured ...

Eukaryotic Initiation Factor 4 (eIF4) is a group of factors that activates mRNA for translation and recruit 43S preinitiation complex (PIC) to the mRNA 5′ end, forming the 48S PIC. The eIF4 factors ...

Although this function of recruiting the initiator tRNA was originally ascribed to another factor, eIF2A, it was later disproven and shown to belong to eIF2. Nonetheless, eIF2A is still considered a ...

This valuable study shows previously unappreciated binding of the eukaryotic translation initiation factor 3 (eIF3) to the poly(A) tail proximal portion of 3' untranslated regions (UTRs) of mRNAs that ...

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