A decade ago this past June, my sister died at the National Institutes of Health. I still have faith in them, and I hope that the country does, too. When she was 10 years old, floaters appeared in ...

Cabozantinib in patients (pts) with non-locally pretreated brain metastases (BM) from renal cell carcinoma (RCC): Results of the multicenter CABRAMET phase II trial (NCT03967522). Evaluating the ...

The EC conditionally approved Merck’s Welireg for certain VHL disease-associated tumors and advanced RCC after two or more prior treatments. Approval is based on data from the LITESPARK-004 and ...

Belzutifan is conditionally approved in the EU for VHL disease-associated tumors and advanced clear cell RCC after prior therapies. The LITESPARK-004 trial reported a 49% objective response rate in ...

The treatment of adult patients with von Hippel-Lindau (VHL) disease who require therapy for associated, localized renal cell carcinoma (RCC), central nervous system (CNS) hemangioblastomas, or ...

The treatment of adult patients with von Hippel-Lindau (VHL) disease who require therapy for associated, localized renal cell carcinoma (RCC), central nervous system (CNS) hemangioblastomas, or ...

“The approval of WELIREG in the EU introduces the first and only systemic treatment option for adult patients with certain VHL disease-associated tumors for whom localized procedures are ...

The approval includes patients with VHL-associated localized renal cell carcinoma, central nervous system (CNS) hemangioblastomas, or pancreatic neuroendocrine tumors for whom localized procedures are ...

SESAUA annual meeting featured a kidney cancer session and a presentation by Dr. Robert Smith discussing how age and tumor ...

pending additional clinical data from LITESPARK-004 and another ongoing Phase 2 trial of WELIREG in patients with certain VHL disease-associated tumors. The FDA approved Welireg in August 2021 for ...

Unfortunately, patients with VHL disease are not referred early to specialized centers after the first tumor diagnosis. Thus, most patients have VHL tumors at the time of diagnosis. After the patients ...