However, even protective ventilation strategies applying minimal mechanical stress may evoke ventilator-induced lung injury (VILI). Adjuvant pharmacological strategies in addition to lung-protective ...

while limiting peak airway pressures to minimize ventilator-associated lung injury. Controversy exists regarding both the timing and criteria that should be utilized for implementation of HFV ...

A New Ventilator-on-a-Chip Model to Study Lung Damage Sep. 19, 2024 — Scientists are now able to directly compare the different kinds of injury that mechanical ventilation causes to cells in the ...

12 Infectious Diseases Translational Research Programme, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore Introduction Ventilator-associated ...

Future studies of the effect of exogenous surfactant in children and adults with ARDS should use the same surfactant and include a study design that can stratify direct versus indirect lung injury.

Objective To investigate the effects of lycopene supplementation on inflammation, lung histopathology and systemic DNA damage in an experimentally induced lung injury model, ventilated by conventional ...

Nevertheless, several treatments are under development and have shown promise in murine models of lung injury.86 GDC-2394 is another NLRP3 inhibitor that was investigated in NLRP3-associated ...

Therefore, this study demonstrated that sufentanil can inhibit apoptosis associated with lung injury in sepsis. Apoptosis and inflammation do not occur in isolation in ALI and there is a complex ...

In conclusion, the results of the present study suggest that DEX ameliorates CLP-induced liver injury to some extent by enhancing autophagy. These data also suggest that regulating autophagy levels ...

Neural Mechanisms of Sleep-Dependent Motor Learning Revealed in New Study on Brain Injury Rehabilitation ... may not be associated with long-term cognitive risks for non-professional athletes ...