The body instinctively responds to external stimuli by increasing energy metabolism and initiating immune responses upon receiving stress signals. Corticosterone (CORT), a glucocorticoid (GC) that ...

Initially, the various programmed death mechanisms were considered to be mutually independent, however, this perspective was challenged by the investigation of PANoptosis, which involves TNF-α and IFN ...

其他 DNA 传感器：IFI16 和 DDX41 等也参与 DNA 感应过程，它们与 STING 相互作用，增强 I 型 IFN 反应和 NF-κB 激活。Z-DNA 结合蛋白 1（ZBP1）能诱导 TBK1-IRF3-IFN I 和 NF-κB 信号通路，促进炎性小体激活和细胞死亡。此外，还有一些 DNA 结合蛋白与 DNA 诱导的 IFN 产生相关 ...

本文聚焦胃癌（GC），深入剖析 Toll 样受体（TLR）家族在其中的多种作用，极具科研价值。 Toll 样受体（TLR）家族在胃癌（GC）中的多重作用 胃癌（Gastric cancer，GC）作为一种严重威胁人类健康的恶性肿瘤，其发生发展是一个极为复杂的过程。众多因素相互交织 ...