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肠道里的“压力传感器”Cell:新研究揭示压力感应蛋白PIEZO1驱动肠道 ...
研究发现,PIEZO1蛋白就像肠道的“压力传感器”,能够感知肠道内的机械力变化,并协调肌肉收缩的节奏。当研究人员通过基因改造让小鼠肠道中的PIEZO1“罢工”时,它们的肠道在压力下无法正常收缩,消化速度明显变慢。相反,当用光激活携带PIEZO1的神经细胞时,小鼠排泄速度直接翻倍——仿佛按下了肠道的“加速键”。
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