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15 天
化疗耐药难题的新突破:βTrCP1 在清除衰老细胞中的关键作用
衰老诱导剂顺铂处理促进 βTrCP1 过表达细胞死亡 :顺铂是一种广泛用于治疗实体肿瘤的化疗药物,但它可能导致肿瘤细胞进入衰老状态。研究人员用不同浓度的顺铂处理细胞,确定了能诱导细胞衰老的最佳浓度。实验结果显示,在顺铂诱导衰老的情况下,βTrCP1 过表达的细胞数量明显减少,出现了细胞死亡的现象。在三维细胞培养中,过表达 βTrCP1 ...
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