Beijing Diabetes Institute, Beijing Key Laboratory of Diabetes Research and Care, Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, P. R. China These ...

骨缺损发病率上升，现有治疗方法存局限。研究人员开展纳米氧化锌（nZnO）促进骨再生机制研究，发现 nZnO 激活 AMPK-ULK1 通路诱导自噬促进骨再生，且与间充质干细胞（MSCs）联用效果更佳，为骨缺损治疗提供新策略。

Nowadays, the prevalence of sedentary lifestyles and high-caloric diets leads to an imbalance between energy intake and ...

Glycolytic capacity efforts are short, high-intensity efforts lasting 1–3 minutes where glycolysis is the primary energy ...

进一步机制研究表明，AMPK通过双重机制：抑制自噬小体积累与激活天然免疫反应，协同形成抗病毒防线。AMPK通过结合TBK1蛋白激活干扰素刺激基因（ISGs），且这一过程独立于传统的JAK-STAT1通路，凸显其独特的免疫调控路径。此外，AMPK的激活 ...