Immunoprecipitation coupled with mass spectrometry (IP-MS) assays uncovered that ORMDL3 binds to USP10 (Ubiquitin-Specific Protease 10), which forms a complex with and stabilizes RIG-I through ...

AMP-activated protein kinase (AMPK), as a key regulator of cellular energy metabolism, influences multiple pathological processes associated with MASLD. This review systematically summarizes the ...

那么问题来了：DCAF7是不是通过招募一个“去泛素化小能手”来帮G3BP1“续命”呢？ 果然！通过IP-MS实验，我们发现USP10（一种去泛素化酶）是DCAF7的潜在合作伙伴。外源性和内源性Co-IP实验都证实了这一点（图2a-b）！DCAF7和USP10真的可以相互作用！🎉 第二步 ...

Department of Pharmacy and Institute of Inflammation, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital (X.H., Y.Z., Y.W., G.L.), Hangzhou ...

This definition makes it clear that myokines have a range of effects throughout the body. In fact, the influence of IL-6 on metabolism via central metabolic signalling molecule 5′ adenosine ...