ATP-competitive small-molecule inhibitors of ... kinases — GSK3β (glycogen synthase kinase 3β, also known as tau protein kinase I), CDK5 (cyclin-dependent kinase 5, also known as tau protein ...

When exposed to glutamate, the organoids—particularly the ones derived from patients with neurodegenerative ...

Abnormal accumulation of tau protein in the brain has been associated with neurodegeneration and cognitive decline in AD patients. BIIB080 is an investigational antisense oligonucleotide therapy ...