Previously we demonstrated an approach to introduce genetic diversity in antibody libraries, where diverse natural CDRs are combined into an antibody framework 11, using only CDR-encoding gene ...

Figure 1: Recombination of V,D, and J Germline Genes into a Functional Antibody (Market and F. Nina Papavasiliou, PLos Biology 1:24-27 Figure 2. Map of the 1Mb human Immunoglobulin heavy chain locus ...

Existing monoclonal antibody development technologies, such as hybridoma technology, suffer from a loss of diversity due to cell fusion efficiency, and phage display technology creates antibodies ...

Scientists from Banaras Hindu University (BHU) are conducting a groundbreaking study at the ongoing Maha Kumbh in Prayagraj to analyse the genetic diversity of attendees and assess immunity levels ...