with a coverage of up to 10 1 native antibody fragments (next-generation-sequencing-verified diversity). By performing the whole antibody-discovery process in vitro and bypassing animal ...

and J Germline Genes into a Functional Antibody (Market and F. Nina Papavasiliou, PLos Biology 1:24-27 Figure 2. Map of the 1Mb human Immunoglobulin heavy chain locus (IgH) showing the high density of ...

Existing monoclonal antibody development technologies, such as hybridoma technology, suffer from a loss of diversity due to cell fusion efficiency, and phage display technology creates antibodies ...