Multi-laser picodroplets can be used in single cell analysis, sorting and dispensing - discover how in this article.

Objectives In the complex panorama of autoimmune diseases, the characterisation of pivotal contributing autoantibodies that are involved in disease progression remains challenging. This study aimed to ...

We examined whether it is possible to directly detect citrullinated antigens in the serum of rheumatoid arthritis (RA) patients using a monoclonal antibody (mAb) designed to be specific for ...

3) Biolojic Design: Founded in 2009, the Israeli company uses a structure-based approach, where their model is trained on millions of Antibody-Antigen pairs in order to identify a template ...

Studies have shown that certain beads carry more antigen than other beads, thus rendering detection of some antibodies more sensitive than others. [12] Furthermore, density differences between a ...

Anti-CD19 chimeric antigen receptor (CD19-CAR)-engineered T cells are approved therapeutics for ... a transmembrane domain-dependent heterodimeric association of the CAR with the endogenous CD28 ...

Recognition of specific antigen through the B-cell receptor (BCR) stimulates the activation of B cells, which ultimately results in the production of high-affinity antibodies and the provision of ...

Subsets of the ANA blood tests are sometimes used to determine the specific autoimmune disease. For this purpose, a doctor may order anti-dsDNA, anti-Sm, Sjögren's antigens (SSA, SSB), Scl-70 ...

A thyroglobulin antibody (TgAb) test looks for certain antibodies that attack the thyroid. The presence of TbAb in high levels may indicate that someone has an autoimmune condition. To conduct a ...

SFRs are currently diagnosed by looking for telltale antibodies in the bloodstream ... nanoparticle reporters were used along with specific antigens that work against the enzyme the team had ...

Oregon Health & Science University is dedicated to improving the health and quality of life for all Oregonians through excellence, innovation and leadership in health care, education and research.