VILI 不仅是 ARDS 的诱因，还会严重影响患者的预后。为了预防 VILI，国际上制定了肺保护性通气策略，比如控制潮气量在 6 - 8ml/kg、峰值通气压力低于 30mbar、使用高呼气末正压（PEEP）、允许一定程度的高碳酸血症等。然而，目前对于最佳 PEEP 水平以及 PEEP 对肺 ...

*图片来自网络2025年2月28日，欧洲药品管理局（EMA）发布了修订版《急性呼吸窘迫综合征（ARDS）治疗药物临床研究指南》征求意见稿，征求意见截至2025年5月31日。急性呼吸窘迫综合征（ARDS）是一种严重的肺部疾病，通常由系统性炎症反应综合征 ...

More specifically related to your question, different levels of PEEP have been tried in treating ALI/ARDS patients. In the most recent study, again published by the ARDS Network Investigators ...

The following is a summary of “Subphenotyping prone position responders with machine learning,” published in the March 2025 issue of Critical Care by Fosset et al. Researchers conducted a retrospectiv ...

Of 789 patients without ARDS on the first day of mechanical ventilation ... 95% CI, 1.2 to 1.7); PEEP (OR, 1.4 per SD; 95% CI, 1.2 to 1.7); sepsis (OR, 1.95; 95% CI, 1.3 to 2.9); VT (OR, 1.4 ...